endogenous cannabinoid造句

• Paracetamol also modulates the endogenous cannabinoid system.
• Moreover, modulation of the endogenous cannabinoid system in the gastrointestinal tract may provide a useful therapeutic target for gastrointestinal disorders.
• In 1992, he and William Anthony Devane isolated and first described the structure of anandamide, an endogenous cannabinoid neurotransmitter.
• Deoxycholic acid binds and activates the membrane enzyme NAPE-PLD, which catalyzes the release of the endogenous cannabinoid anandamide and other N-acylethanolamines.
• Paracetamol is metabolised to AM404, a compound with several actions; what is most important is that it inhibits the reuptake of the endogenous cannabinoid / vanilloid anandamide by neurons.
• It has been demonstrated that when cannabinoid receptors are blocked with synthetic antagonists, paracetamol's analgesic effects are prevented, suggesting its pain-relieving action involves the endogenous cannabinoid system.
• As for the anecdotes about exercise, they likely experienced a " runner's high " due to their bodies releasing endorphins, which are endogenous opioid agonists, along with anandamide and other endogenous cannabinoid agonists.
• "' Entourage effect "'is a phrase that was introduced in cannabinoid science in 1998 by S . Ben-Shabat, with Raphael Mechoulam, to represent a novel endogenous cannabinoid molecular regulation route.
• The exact biosynthesis of NaGly is not completely understood, but there are two proposed pathways found in vitro for its biosynthesis : 1 ) enzymatically regulated conjugation of arachidonic acid and glycine and 2 ) the oxidative metabolism of the endogenous cannabinoid anandamide.